Terminology Service for NFDI4Health
Cylindruria
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http://purl.obolibrary.org/obo/HP_0012615
The presence of renal casts (cylindrical, cigar-shaped structures produced by the kidney in certain disease states) in the urine. [ http://www.ncbi.nlm.nih.gov/pubmed/26079824 ]
Term info
Label
Cylindruria
Synonyms
- Urinary casts
comment
Urinary casts are formed in the distal convoluted tubule or the collecting duct by solidification of protein in the lumen of the kidney tubules. The casts are suibsequently eliminated via the urine and may be seen by microscopy of the urine sediment. A large number of casts can indicate kidney disease. Urinary casts are composed of Tamm-Horsfall protein, which is a mucoprotein that is secreted by the distal loop of Henle.
created by
peter
creation date
2014-01-17T12:03:19Z
has obo namespace
human_phenotype
id
HP:0012615