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Enlarged peripheral nerve

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Increase in size of a peripheral nerve. This finding can be appreciated by palpation along the axis of the nerve. [ ]

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Enlarged peripheral nerve

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This feature can be appreciated by imaging studies (magnetic resonancy tomography), by palpation along the axis of a nerve, and by biopsy, and may be caused by axonal swelling or by myelin thickening. The differential diagnosis of enlarged peripheral nerves includes leprosy, hereditary motor and sensory neuropathy type 1 (about 30% of patients), but not type 2 (the axonal form), some other polyneuropathies, neurofibromatosis, and nerve tumors. A good review is available in Practical Neurology, 2003,3:40-45 by Michael Donaghy (no pubmed id).

created by

peter

creation date

2014-02-01T12:44:16Z

has obo namespace

human_phenotype

has related synonym

Enlarged peripheral nerves

id

HP:0012645

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