Terminology Service for NFDI4Health

integrin alpha-M

Go to external page http://purl.obolibrary.org/obo/PR_000001012


An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1. [ https://www.uniprot.org/uniprot/P11215 ]

Term info

Label

integrin alpha-M

Synonyms
  • CD11 antigen-like family member B
  • CD11b
  • CR-3 alpha chain
  • ITGAM
  • cell surface glycoprotein MAC-1 subunit alpha
  • leukocyte adhesion receptor MO1
  • neutrophil adherence receptor
database cross reference
comment

Category=gene. Requested by=CL.

has related synonym

CR3A, CD11B

id

PR:000001012

Term relations