Terminology Service for NFDI4Health
JSON

islet of Langerhans

Go to external page http://purl.obolibrary.org/obo/UBERON_0000006

the clusters of hormone-producing cells that are scattered throughout the pancreas [ http://www.informatics.jax.org/searches/AMA.cgi?id=MA:0000127 ]

Term info

Label

islet of Langerhans

Synonyms
  • pancreatic insula
  • pancreatic islet
database cross reference
Subsets

uberon_slim, efo_slim, pheno_slim

depicted by

http://upload.wikimedia.org/wikipedia/commons/9/99/Gray1105.png

external definition

Anatomical structure which consists of glands developed from pancreatic ducts in the larvae and secrete insulin.[AAO]

fma set term

http://purl.obolibrary.org/obo/FMA_76489

has related synonym

island of pancreas, island of Langerhans, islets of Langerhans

homology notes

Mammals, birds, reptiles and amphibians have a pancreas with similar histology and mode of development, while in some fish, the islet cells are segregated as Brockmann bodies.[well established][VHOG]

id

UBERON:0000006

taxon notes

A primitive exocrine pancreas can be found in holocephalan cartilaginous fish; a pancreatic duct directly ending in the gut lumen is connected to a glandular structure made of exocrine cells and associated with cell islets, which comprises three different hormone-producing cell types: insulin, somatostatin and glucagon (Yui and Fujita, 1986)