Terminology Service for NFDI4Health

neural nucleus

Go to external page http://purl.obolibrary.org/obo/UBERON_0000125


A spatially aggregated collection of nerve cell bodies in the CNS, consisting of one or more subpopulations that share cell type, chemical phenotype, and connections, and including nearby cells that share the same cell type, chemical phenotype, and connections. (CUMBO) [ ]

Term info

Label

neural nucleus

Synonyms
  • nervous system nucleus
  • neuraxis nucleus
  • neuronal nucleus
  • nucleus of CNS
database cross reference
Subsets

cumbo

external definition

Anatomical structure consisting of a discrete aggregate of neuronal soma[GO][GO_REF:0000021].

external ontology notes

Proposed CUMBO def from MM: A subcortical part of the nervous system consisting of a relatively compact group of cells that is distinguishable histologically that share a commonality of cytoarchitecture, chemoarchitecturel and connectivity. (comments: I put in 'subcortical' because I don't think we consider either the cerebellar cortex or cerebral cortex to be nuclei. Some people distinguish between a nucleus and a laminar structure (see Wikipedia definition). However, there are structures identified as nuclei that are laminar, e.g., lateral geniculate nucleus, although they are not laminated in all species. Also, I put in 'relatively compact' and 'distiguishable by histology' because we have groups of cells, e.g., cholinergic cell groups, doparminergic cell groups that are related on the 3 criteria but which we don't tend to consider nuclei because they don't occupy an easily defined territory. But all is open to debate.

has related synonym

nucleus of neuraxis

id

UBERON:0000125