Terminology Service for NFDI4Health

midbrain

Go to external page http://purl.obolibrary.org/obo/UBERON_0001891


The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)[GO]. [ http://amigo.geneontology.org/amigo/term/GO:0030901 ]

Term info

Label

midbrain

database cross reference
Subsets

uberon_slim, efo_slim, pheno_slim, vertebrate_core

abbreviation
MB [ BIRNLEX : 1667 NIFSTD : NeuroNames_abbrevSource ]

depicted by

http://upload.wikimedia.org/wikipedia/commons/f/f9/Human_brain_inferior_view_description.JPG

editor note

developmental relationships need revised

external definition

The brain region between the forebrain anteriorly and the hindbrain posteriorly, including the tectum dorsally and the midbrain tegmentum ventrally. Kimmel et al, 1995.[TAO], Middle part of the brain composed of the optic tectum and penducular region.[AAO]

external ontology notes

part of brainstem in ABA - we reject this in favor of ISBN:0471888893 which has an implicit overlaps relationships

has related synonym

mesencephalon

has relational adjective

mesencephalic

homology notes

Fine structural, computerized three-dimensional (3D) mapping of cell connectivity in the amphioxus nervous system and comparative molecular genetic studies of amphioxus and tunicates have provided recent insights into the phylogenetic origin of the vertebrate nervous system. The results suggest that several of the genetic mechanisms for establishing and patterning the vertebrate nervous system already operated in the ancestral chordate and that the nerve cord of the proximate invertebrate ancestor of the vertebrates included a diencephalon, midbrain, hindbrain, and spinal cord.[well established][VHOG]

id

UBERON:0001891