Terminology Service for NFDI4Health
atrioventricular canal
Go to external page
http://purl.obolibrary.org/obo/UBERON_0002087
The part of the heart connecting the atrium to the cardiac ventricle[ZFA]. In the developing heart, the constriction between the atrium and ventricle constitutes the atrial canal, and indicates the site of the future atrioventricular valves[WP]. [ https://github.com/obophenotype/uberon/issues/38 http://en.wikipedia.org/wiki/Atrioventricular_canal ]
Term info
Label
atrioventricular canal
Synonyms
- AV canal
- AVC
- atrial canal
- atrio-ventricular canal
Subsets
uberon_slim, pheno_slim, vertebrate_core
contributor
https://github.com/cmungall, https://github.com/mellybelly, https://github.com/rfoulger
depicted by
http://upload.wikimedia.org/wikipedia/commons/d/d8/Gray464.png
development notes
The right side of the AVC becomes the tricuspid valve whereas the left side of the AVC will become the bicuspid valve
external definition
The canal connecting the primitive atrium and ventricle in fishes and amniotes embryo. [TFD][VHOG]
external ontology notes
this is a lumen in EHDAA2
function notes
In the embryo, the atrioventricular canal delays the impulse from atrium to ventricle[PMID:22984480]
has obo namespace
uberon
has related synonym
canalis atrioventricularis, ependymal canal
homology notes
The heart is the first organ to form and function in a vertebrate. (...) Septation of the AV canal is initiated with the formation of inferior and superior endocardial cushions in response to signaling from the overlying myocardium. (...) Analysis of zebrafish mutants with cardiovascular defects uncovered a previously unexpected level of conservation between zebrafish and human cardiovascular physiology.[uncertain][VHOG]
id
UBERON:0002087