Terminology Service for NFDI4Health
cranial neural crest
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http://purl.obolibrary.org/obo/UBERON_0003099
neural crest cells (NCCs) originating in the anterior part of the developing embryo and residing between the mid-diencephalon and the forming hindbrain; cranial NCCs migrate dorsolaterally to form the craniofacial mesenchyme that differentiates into various craniofacial cartilages and bones, cranial neurons, glia, and connective tissues of the face; these cells enter the pharyngeal pouches and arches where they give rise to thymic cells, bones of the middle ear and jaw (mandible), and the odontoblasts of the tooth primordia; like their counterparts in the trunk, cranial NCCs also contribute to the developing peripheral nervous system, along with the pigmented cell (i.e. melanocyte) lineage. [ http://www.informatics.jax.org/accession/anna ]
Term info
Label
cranial neural crest
Synonyms
- CNC
- cephalic neural crest
- cranial NCC population
- head NCC population
Subsets
uberon_slim, efo_slim, vertebrate_core
external definition
Neural crest that is part of the head.[TAO], Anterior most portion of the neural crest. Migrates in three highly conserved streams: mandibular, hyoid and branchial.[AAO]
has obo namespace
uberon
has related synonym
crista neuralis cranialis, head neural crest, head crest
homology notes
We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG]
id
UBERON:0003099