Terminology Service for NFDI4Health
presumptive hindbrain
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http://purl.obolibrary.org/obo/UBERON_0007277
The rhombencephalon (or hindbrain) is a developmental categorization of portions of the central nervous system in vertebrates. The rhombencephalon can be subdivided in a variable number of transversal swellings called rhombomeres. In the human embryo eight rhombomeres can be distinguished, from caudal to rostral: Rh7-Rh1 and the isthmus (the most rostral rhombomere). A rare disease of the rhombencephalon, 'rhombencephalosynapsis' is characterized by a missing vermis resulting in a fused cerebellum. Patients generally present with cerebellar ataxia. The caudal rhombencephalon has been generally considered as the initiation site for neural tube closure. [ http://en.wikipedia.org/wiki/Rhombencephalon ]
Term info
Label
presumptive hindbrain
Synonyms
- presumptive rhombencephalon
Subsets
efo_slim
editor note
TODO - unify naming conventions
external definition
The embryonic rhombencephalon can be subdivided in a variable number of transversal swellings called rhombomeres. Rhombomeres Rh7-Rh4 form the myelencephalon that will give the medulla oblongata. Rhombomeres Rh3-Rh1 form the metencephalon that will form the pons and the cerebellum[NPX:PDR].
has obo namespace
uberon
has related synonym
future hindbrain, rhombencephalon, embryonic rhombencephalon
id
UBERON:0007277