Terminology Service for NFDI4Health

germinal center

Go to external page http://purl.obolibrary.org/obo/UBERON_0010754


A collection of activated B cells at the center of a secondary follicle, formed after B cells become activated and migrate to the center. [ https://orcid.org/0000-0002-6601-2165 http://purl.obolibrary.org/obo/CL_tm http://en.wikipedia.org/wiki/Germinal_center ]

Term info

Label

germinal center

Synonyms
  • central zone of follice
  • light zone of follicle
  • reaction center of follicle
database cross reference
comment

A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation.[GO]

depicted by

http://purl.obolibrary.org/obo/Germinal_center.svg

has related synonym

lymhpoid nodule, nodule

id

UBERON:0010754