Terminology Service for NFDI4Health

renin-angiotensin system

Go to external page http://purl.obolibrary.org/obo/UBERON_0018229


A system consisting of renin, angiotensin-converting enzyme, and angiotensin II. Renin, an enzyme produced in the kidney, acts on angiotensinogen, an alpha-2 globulin produced by the liver, forming angiotensin I. The converting enzyme contained in the lung acts on angiotensin I in the plasma converting it to angiotensin II, the most powerful directly pressor substance known. It causes contraction of the arteriolar smooth muscle and has other indirect actions mediated through the adrenal cortex. [ ]

Term info

Label

renin-angiotensin system

database cross reference
Subsets

pheno_slim

curator notes

may be replaced by a GO process in future

has related synonym

renin-angiotensin-aldosterone system, renin angiotensin aldosterone system, renin angiotensin system, renin-angiotensin system

id

UBERON:0018229

Term relations