Terminology Service < Semantic Lookup Platform

All terms in HP

Label	Id	Description
regulation of translation	GO_0006417	[Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.]
translation	GO_0006412	[The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.]
stem cell division	GO_0017145	[The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types.]
cell division	GO_0051301	[The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.]
drug metabolic process	GO_0017144	[The chemical reactions and pathways involving a drug, a substance used in the diagnosis, treatment or prevention of a disease; as used here antibiotic substances (see antibiotic metabolism) are considered to be drugs, even if not used in medical or veterinary practice.]
cellular metabolic process	GO_0044237	[The chemical reactions and pathways by which individual cells transform chemical substances.]
corticotropin	CHEBI_3892	[A polypeptide hormone produced and secreted by the pituitary gland comprising 39 amino acid residues coupled in a linear sequence. The N-terminal 24-amino acid segment is identical in all species and contains the adrenocorticotrophic activity. Corticotropin stimulates the cortex of the adrenal gland and boosts the synthesis of corticosteroids, mainly glucocorticoids but also sex steroids (androgens). It is used in the treatment of certain neurological disorders such as infantile spasms and multiple sclerosis, and diagnostically to investigate adrenocortical insufficiency.]
peptide hormone	CHEBI_25905	[Any peptide with hormonal activity in animals, whether endocrine, neuroendocrine, or paracrine.]
biomacromolecule	CHEBI_33694	[A macromolecule formed by a living organism.]
polypeptide	CHEBI_15841	[A peptide containing ten or more amino acid residues.]
diagnostic agent	CHEBI_33295	[A substance administered to aid diagnosis of a disease.]
regulation of oxidoreductase activity	GO_0051341	[Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.]
negative regulation of monooxygenase activity	GO_0032769	[Any process that stops or reduces the activity of a monooxygenase.]
negative regulation of oxidoreductase activity	GO_0051354	[Any process that stops or reduces the rate of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.]
B cell activation	GO_0042113	[The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.]
lymphocyte activation	GO_0046649	[A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor.]
alpha-beta T cell receptor complex	GO_0042105	[A T cell receptor complex in which the TCR heterodimer comprises alpha and beta chains, associated with the CD3 complex; recognizes a complex consisting of an antigen-derived peptide bound to a class I or class II MHC protein.]
T cell receptor complex	GO_0042101	[A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains.]
5-oxoprolinase (ATP-hydrolyzing) activity	GO_0017168	[Catalysis of the reaction: 5-oxo-L-proline + ATP + 2 H(2)O = L-glutamate + ADP + 2 H(+) + phosphate.]
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	GO_0016812	[Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amide.]