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Alzheimer Disease

Go to external page http://purl.bioontology.org/ontology/MESH/D000544

A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

Instance info

Synonyms

Akute senile Demenz mit Verwirrtheit (DE), Presenile Alzheimer Dementia, Dementias, Alzheimer, Demenz, Alzheimer-Typ (DE), Alzheimer-Krankheit, später Beginn (DE), Früher Beginn der Alzheimer-Krankheit (DE), Alzheimer Syndrome, Acute Confusional Senile Dementia, Alzheimer-Krankheit, früher Beginn (DE), Alzheimer Diseases, Familial (FAD), Fokaler Beginn der Alzheimer-Krankheit (DE), Demenz, primär degenerative präsenile (DE), Early Onset Alzheimer Disease, Dementia senilis (DE), Später Beginn der Alzheimer-Krankheit (DE), Primary Senile Degenerative Dementia, Dementia, Presenile, Senile Demenz, Alzheimer-Typ (DE), Alzheimer Dementias, Dementia, Alzheimer, Dementia, Alzheimer-Type (ATD), Alzheimer's Disease, Focal Onset, Präsenile Alzheimer-Demenz (DE), Senile Dementia, Acute Confusional, Demenz, primär degenerative senile (DE), Familial Alzheimer Disease (FAD), Alzheimer Disease, Early Onset, Dementia, Primary Senile Degenerative, Demenz, senile (DE), Demenz, präsenile (DE), Alzheimer-Krankheit, fokaler Beginn (DE), Alzheimer Type Senile Dementia, Focal Onset Alzheimer's Disease, Dementia, Alzheimer Type, Late Onset Alzheimer Disease, Alzheimer Dementia, Primär degenerative senile Demenz (DE), Alzheimer Disease, Familial (FAD), Alzheimer Sclerosis, Presenile Dementia, Dementia, Senile, Senile Dementia, Dementia praesenilis (DE), Alzheimer Type Dementia, Alzheimer Disease, Late Onset, Sclerosis, Alzheimer, Präsenile Demenz (DE), Alzheimer-Type Dementia (ATD), Alzheimer's Disease, Senile Dementia, Alzheimer Type, Alzheimer-Krankheit (DE), Familial Alzheimer Diseases (FAD), Alzheimer Type Dementia (ATD)

AQL

BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI

DC

1

DX

19840101

FX

D020232,D016229,D016900,D018888,D016875,D016657,D016564

HN

1998(1963); for DEMENTIA, PRESENILE and DEMENTIA, PRIMARY DEGENERATIVE SENILE use DEMENTIA 1981-1999; for DEMENTIA SENILE use DEMENTIA 1966-1999

MDA

19990101

MMR

20170224

MN

F03.615.400.100,C10.574.945.249,C10.228.140.380.100

PM

1998; see ALZHEIMER'S DISEASE 1984-1997, see DEMENTIA, PRESENILE 1967-1983, see PSYCHOSES, PRESENILE 1963-1966; for DEMENTIA PRESENILE and DEMENTIA, PRIMARY DEGENERATIVE, SENILE see DEMENTIA 1981-1999; for DEMENTIA, SENILE see DEMENTIA 1966-1999

QB

http://purl.bioontology.org/ontology/MESH/Q000175,http://purl.bioontology.org/ontology/MESH/Q000097,http://purl.bioontology.org/ontology/MESH/Q000196,http://purl.bioontology.org/ontology/MESH/Q000151,http://purl.bioontology.org/ontology/MESH/Q000150,http://purl.bioontology.org/ontology/MESH/Q000191,http://purl.bioontology.org/ontology/MESH/Q000139,http://purl.bioontology.org/ontology/MESH/Q000534,http://purl.bioontology.org/ontology/MESH/Q000235,http://purl.bioontology.org/ontology/MESH/Q000378,http://purl.bioontology.org/ontology/MESH/Q000532,http://purl.bioontology.org/ontology/MESH/Q000652,http://purl.bioontology.org/ontology/MESH/Q000134,http://purl.bioontology.org/ontology/MESH/Q000178,http://purl.bioontology.org/ontology/MESH/Q000453,http://purl.bioontology.org/ontology/MESH/Q000276,http://purl.bioontology.org/ontology/MESH/Q000000981,http://purl.bioontology.org/ontology/MESH/Q000473,http://purl.bioontology.org/ontology/MESH/Q000451,http://purl.bioontology.org/ontology/MESH/Q000517,http://purl.bioontology.org/ontology/MESH/Q000382,http://purl.bioontology.org/ontology/MESH/Q000469,http://purl.bioontology.org/ontology/MESH/Q000601,http://purl.bioontology.org/ontology/MESH/Q000821,http://purl.bioontology.org/ontology/MESH/Q000523,http://purl.bioontology.org/ontology/MESH/Q000401,http://purl.bioontology.org/ontology/MESH/Q000201,http://purl.bioontology.org/ontology/MESH/Q000662,http://purl.bioontology.org/ontology/MESH/Q000145,http://purl.bioontology.org/ontology/MESH/Q000266,http://purl.bioontology.org/ontology/MESH/Q000188,http://purl.bioontology.org/ontology/MESH/Q000628,http://purl.bioontology.org/ontology/MESH/Q000209,http://purl.bioontology.org/ontology/MESH/Q000208,http://purl.bioontology.org/ontology/MESH/Q000503

RO

http://purl.bioontology.org/ontology/MESH/D016657,http://purl.bioontology.org/ontology/MESH/D016229,http://purl.bioontology.org/ontology/MESH/D016900,http://purl.bioontology.org/ontology/MESH/D016875,http://purl.bioontology.org/ontology/MESH/D018888,http://purl.bioontology.org/ontology/MESH/D020232,http://purl.bioontology.org/ontology/MESH/D016564

SIB

http://purl.bioontology.org/ontology/MESH/D057174,http://purl.bioontology.org/ontology/MESH/D006816,http://purl.bioontology.org/ontology/MESH/D018888,http://purl.bioontology.org/ontology/MESH/D055956,http://purl.bioontology.org/ontology/MESH/D007562,http://purl.bioontology.org/ontology/MESH/D020232,http://purl.bioontology.org/ontology/MESH/D013494,http://purl.bioontology.org/ontology/MESH/D015140,http://purl.bioontology.org/ontology/MESH/D020961,http://purl.bioontology.org/ontology/MESH/D015526

TERMUI

T010820,T365981,T369933,T366224,T365982,T365983,T366225,T366226,T000915952,T843728,T843727,T001655,T840888,T001654,T365967,T365968,T840887,T010818,T366227,T365964,T365965,T369934,T365966

TH

NLM (2018),GHR (2014),ORD (2010),OMIM (2013),NLM (1966),NLM (2000),NLM (1998),NLM (1967),NLM (1975)

cui

C0750901,C0750900,C0276496,C0011265,C0002395,C0546126,C0494463

hasSTY

http://purl.bioontology.org/ontology/STY/T047,http://purl.bioontology.org/ontology/STY/T048

mapped from

http://purl.bioontology.org/ontology/MESH/C565728,http://purl.bioontology.org/ontology/MESH/C564329,http://purl.bioontology.org/ontology/MESH/C563834,http://purl.bioontology.org/ontology/MESH/C565228,http://purl.bioontology.org/ontology/MESH/C566999,http://purl.bioontology.org/ontology/MESH/C565325,http://purl.bioontology.org/ontology/MESH/C566998,http://purl.bioontology.org/ontology/MESH/C564622,http://purl.bioontology.org/ontology/MESH/C566578,http://purl.bioontology.org/ontology/MESH/C563254,http://purl.bioontology.org/ontology/MESH/C566465,http://purl.bioontology.org/ontology/MESH/C566299,http://purl.bioontology.org/ontology/MESH/C566298,http://purl.bioontology.org/ontology/MESH/C565078,http://purl.bioontology.org/ontology/MESH/C564330,http://purl.bioontology.org/ontology/MESH/C567463,http://purl.bioontology.org/ontology/MESH/C565251,http://purl.bioontology.org/ontology/MESH/C567000,http://purl.bioontology.org/ontology/MESH/C567022,http://purl.bioontology.org/ontology/MESH/C536596,http://purl.bioontology.org/ontology/MESH/C536599,http://purl.bioontology.org/ontology/MESH/C536598,http://purl.bioontology.org/ontology/MESH/C536595,http://purl.bioontology.org/ontology/MESH/C536594

tui

T048,T047

Instance relations

Types