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Encephalomyelitis, Autoimmune, Experimental

Go to external page http://purl.bioontology.org/ontology/MESH/D004681

An experimental animal model for central nervous system demyelinating disease. Inoculation with a white matter emulsion combined with FREUND'S ADJUVANT, myelin basic protein, or purified central myelin triggers a T cell-mediated immune response directed towards central myelin. The pathologic features are similar to MULTIPLE SCLEROSIS, including perivascular and periventricular foci of inflammation and demyelination. Subpial demyelination underlying meningeal infiltrations also occurs, which is also a feature of ENCEPHALOMYELITIS, ACUTE DISSEMINATED. Passive immunization with T-cells from an afflicted animal to a normal animal also induces this condition. (From Immunol Res 1998;17(1-2):217-27; Raine CS, Textbook of Neuropathology, 2nd ed, p604-5)

Instance info

Synonyms

Experimental Allergic Encephalomyelitis, Encephalomyelitis, Experimental Allergic, Enzephalomyelitis, experimentelle allergische (DE), Experimental Encephalomyelitis, Autoimmune, Experimental Allergic Encephalomyelitides, Autoimmune Encephalomyelitis, Experimental, Encephalomyelitis, Experimental Autoimmune, Experimental Autoimmune Encephalomyelitis, Enzephalomyelitis, experimentelle, autoimmune (DE), Allergic Encephalomyelitis, Experimental, Allergic Encephalomyelitis, Autoimmune Enzephalomyelitis, experimentelle (DE), Enzephalomyelitis, autoimmune, experimentelle (DE), Encephalomyelitis, Allergic, Enzephalomyelitis, allergische (DE), Encephalomyelitis, Autoimmune Experimental, Autoimmune Experimental Encephalomyelitis

AN

coordinate with specific demyelinating disease if pertinent

AQL

BL CF CI CL CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI

DC

1

DX

19660101

HN

2005 (1964)

MDA

19990101

MMR

20130708

MN

C20.111.258.625.300,C10.228.140.695.562.250,E05.598.500.500.500,C10.314.350.250,C10.114.703.300

PM

2005; see ENCEPHALOMYELITIS, EXPERIMENTAL AUTOIMMUNE 2000-2004, see ENCEPHALOMYELITIS, ALLERGIC 1964-1999

QB

http://purl.bioontology.org/ontology/MESH/Q000097,http://purl.bioontology.org/ontology/MESH/Q000175,http://purl.bioontology.org/ontology/MESH/Q000196,http://purl.bioontology.org/ontology/MESH/Q000150,http://purl.bioontology.org/ontology/MESH/Q000191,http://purl.bioontology.org/ontology/MESH/Q000139,http://purl.bioontology.org/ontology/MESH/Q000534,http://purl.bioontology.org/ontology/MESH/Q000378,http://purl.bioontology.org/ontology/MESH/Q000532,http://purl.bioontology.org/ontology/MESH/Q000235,http://purl.bioontology.org/ontology/MESH/Q000652,http://purl.bioontology.org/ontology/MESH/Q000453,http://purl.bioontology.org/ontology/MESH/Q000178,http://purl.bioontology.org/ontology/MESH/Q000134,http://purl.bioontology.org/ontology/MESH/Q000276,http://purl.bioontology.org/ontology/MESH/Q000473,http://purl.bioontology.org/ontology/MESH/Q000000981,http://purl.bioontology.org/ontology/MESH/Q000451,http://purl.bioontology.org/ontology/MESH/Q000517,http://purl.bioontology.org/ontology/MESH/Q000382,http://purl.bioontology.org/ontology/MESH/Q000469,http://purl.bioontology.org/ontology/MESH/Q000821,http://purl.bioontology.org/ontology/MESH/Q000601,http://purl.bioontology.org/ontology/MESH/Q000523,http://purl.bioontology.org/ontology/MESH/Q000401,http://purl.bioontology.org/ontology/MESH/Q000201,http://purl.bioontology.org/ontology/MESH/Q000662,http://purl.bioontology.org/ontology/MESH/Q000145,http://purl.bioontology.org/ontology/MESH/Q000266,http://purl.bioontology.org/ontology/MESH/Q000188,http://purl.bioontology.org/ontology/MESH/Q000628,http://purl.bioontology.org/ontology/MESH/Q000209,http://purl.bioontology.org/ontology/MESH/Q000208,http://purl.bioontology.org/ontology/MESH/Q000503

SIB

http://purl.bioontology.org/ontology/MESH/D009188,http://purl.bioontology.org/ontology/MESH/D009471,http://purl.bioontology.org/ontology/MESH/D009444,http://purl.bioontology.org/ontology/MESH/D009103,http://purl.bioontology.org/ontology/MESH/D004684,http://purl.bioontology.org/ontology/MESH/D004673,http://purl.bioontology.org/ontology/MESH/D020720,http://purl.bioontology.org/ontology/MESH/D002549

TERMUI

T014339,T365221,T014338,T014346,T014347,T014344,T014345,T014340,T014341

TH

NLM (1992),ORD (2010),NLM (2000),NLM (1995),NLM (1964),NLM (1996)

cui

C0014072

hasSTY

http://purl.bioontology.org/ontology/STY/T050

tui

T050

Instance relations

Types