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Leukoencephalopathy, Progressive Multifocal

Go to external page http://purl.bioontology.org/ontology/MESH/D007968

An opportunistic viral infection of the central nervous system associated with conditions that impair cell-mediated immunity (e.g., ACQUIRED IMMUNODEFICIENCY SYNDROME and other IMMUNOLOGIC DEFICIENCY SYNDROMES; HEMATOLOGIC NEOPLASMS; IMMUNOSUPPRESSION; and COLLAGEN DISEASES). The causative organism is JC Polyomavirus (JC VIRUS) which primarily affects oligodendrocytes, resulting in multiple areas of demyelination. Clinical manifestations include DEMENTIA; ATAXIA; visual disturbances; and other focal neurologic deficits, generally progressing to a vegetative state within 6 months. (From Joynt, Clinical Neurology, 1996, Ch26, pp36-7)

Term info

Label

Leukoencephalopathy, Progressive Multifocal

Synonyms
  • Encephalitis, JC Polyomavirus
  • Encephalopathies, JC Polyomavirus
  • Encephalopathy, JC Polyomavirus
  • Enzephalitis, JC-Polyomavirus (DE)
  • JC Polyomavirus Encephalitis
  • JC Polyomavirus Encephalopathy
  • Leukoencephalopathies, Progressive Multifocal
  • Leukoenzephalopathie, progressive multifokale (DE)
  • Multifocal Leukoencephalopathies, Progressive
  • Multifocal Leukoencephalopathy, Progressive
  • Progressive Multifocal Leukoencephalopathies
  • Progressive Multifocal Leukoencephalopathy
  • Progressive multifokale Leukoenzephalopathie (DE)
AQL

BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH TM UR VE VI

DC

1

DX

19730101

HN

1973(1971)

MDA

19990101

MMR

20150702

MN

C02.256.721.500, C10.228.228.245.340.500, C10.228.140.695.750, C10.228.140.430.520.750.500, C02.839.550, C10.314.450, C02.290.575, C02.182.525.500, C10.228.228.399.750.500

PM

1973

QB

http://purl.bioontology.org/ontology/MESH/Q000175, http://purl.bioontology.org/ontology/MESH/Q000097, http://purl.bioontology.org/ontology/MESH/Q000196, http://purl.bioontology.org/ontology/MESH/Q000151, http://purl.bioontology.org/ontology/MESH/Q000150, http://purl.bioontology.org/ontology/MESH/Q000191, http://purl.bioontology.org/ontology/MESH/Q000139, http://purl.bioontology.org/ontology/MESH/Q000534, http://purl.bioontology.org/ontology/MESH/Q000235, http://purl.bioontology.org/ontology/MESH/Q000532, http://purl.bioontology.org/ontology/MESH/Q000378, http://purl.bioontology.org/ontology/MESH/Q000652, http://purl.bioontology.org/ontology/MESH/Q000134, http://purl.bioontology.org/ontology/MESH/Q000453, http://purl.bioontology.org/ontology/MESH/Q000178, http://purl.bioontology.org/ontology/MESH/Q000276, http://purl.bioontology.org/ontology/MESH/Q000473, http://purl.bioontology.org/ontology/MESH/Q000000981, http://purl.bioontology.org/ontology/MESH/Q000451, http://purl.bioontology.org/ontology/MESH/Q000517, http://purl.bioontology.org/ontology/MESH/Q000635, http://purl.bioontology.org/ontology/MESH/Q000382, http://purl.bioontology.org/ontology/MESH/Q000469, http://purl.bioontology.org/ontology/MESH/Q000601, http://purl.bioontology.org/ontology/MESH/Q000821, http://purl.bioontology.org/ontology/MESH/Q000523, http://purl.bioontology.org/ontology/MESH/Q000401, http://purl.bioontology.org/ontology/MESH/Q000201, http://purl.bioontology.org/ontology/MESH/Q000662, http://purl.bioontology.org/ontology/MESH/Q000266, http://purl.bioontology.org/ontology/MESH/Q000145, http://purl.bioontology.org/ontology/MESH/Q000188, http://purl.bioontology.org/ontology/MESH/Q000628, http://purl.bioontology.org/ontology/MESH/Q000209, http://purl.bioontology.org/ontology/MESH/Q000208, http://purl.bioontology.org/ontology/MESH/Q000503

SIB

http://purl.bioontology.org/ontology/MESH/D060486, http://purl.bioontology.org/ontology/MESH/D013344, http://purl.bioontology.org/ontology/MESH/D020803, http://purl.bioontology.org/ontology/MESH/D020804, http://purl.bioontology.org/ontology/MESH/D011021, http://purl.bioontology.org/ontology/MESH/D015266, http://purl.bioontology.org/ontology/MESH/D004671, http://purl.bioontology.org/ontology/MESH/D052879, http://purl.bioontology.org/ontology/MESH/D011129, http://purl.bioontology.org/ontology/MESH/D054319, http://purl.bioontology.org/ontology/MESH/D000386, http://purl.bioontology.org/ontology/MESH/D000453, http://purl.bioontology.org/ontology/MESH/D054038, http://purl.bioontology.org/ontology/MESH/D004683, http://purl.bioontology.org/ontology/MESH/D000163, http://purl.bioontology.org/ontology/MESH/D016097, http://purl.bioontology.org/ontology/MESH/D020278, http://purl.bioontology.org/ontology/MESH/D015140, http://purl.bioontology.org/ontology/MESH/D020279, http://purl.bioontology.org/ontology/MESH/D004859, http://purl.bioontology.org/ontology/MESH/D017590, http://purl.bioontology.org/ontology/MESH/D016181, http://purl.bioontology.org/ontology/MESH/D016182

TERMUI

T368991, T368990, T023751, T368989

TH

NLM (1971), ORD (2010), NLM (2000)

cui

C0023524

hasSTY

http://purl.bioontology.org/ontology/STY/T047

tui

T047