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Polyendocrinopathies, Autoimmune

Go to external page http://purl.bioontology.org/ontology/MESH/D016884

Autoimmune diseases affecting multiple endocrine organs. Type I is characterized by childhood onset and chronic mucocutaneous candidiasis (CANDIDIASIS, CHRONIC MUCOCUTANEOUS), while type II exhibits any combination of adrenal insufficiency (ADDISON'S DISEASE), lymphocytic thyroiditis (THYROIDITIS, AUTOIMMUNE;), HYPOPARATHYROIDISM; and gonadal failure. In both types organ-specific ANTIBODIES against a variety of ENDOCRINE GLANDS have been detected. The type II syndrome differs from type I in that it is associated with HLA-A1 and B8 haplotypes, onset is usually in adulthood, and candidiasis is not present.

Term info

Label

Polyendocrinopathies, Autoimmune

Synonyms
  • AIRE Deficiencies
  • AIRE Deficiency
  • APECED
  • APS Type 1
  • Autoimmune Polyendocrine Syndrome, Type 2
  • Autoimmune Polyendocrine Syndrome, Type II
  • Autoimmune Polyendocrinopathy
  • Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy
  • Autoimmune Polyendocrinopathy Syndrome Type 1
  • Autoimmune Polyendocrinopathy with Candidiasis and Ectodermal Dystrophy
  • Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy
  • Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal-Dystrophy
  • Autoimmune Polyglandular Syndrome Type I
  • Autoimmune Polyglandular Syndrome Type II
  • Autoimmune Polyglandular Syndrome Type III
  • Autoimmune Polyglandular Syndrome, Type 1
  • Autoimmune Polyglandular Syndrome, Type 3
  • Autoimmune Polyglandular Syndrome, Type I
  • Autoimmune Syndrome Type I, Polyglandular
  • Autoimmune Syndrome Type II, Polyglandular
  • Autoimmune Syndrome Type III, Polyglandular
  • Autoimmunsyndrom Typ I, polyglanduläres (DE)
  • Autoimmunsyndrom Typ II, polyglanduläres (DE)
  • Deficiency, AIRE
  • Diabetes Mellitus, Addison Disease, Myxedema
  • Diabetes Mellitus, Addison's Disease, Myxedema
  • Multiple Endocrine Deficiency Syndrome, Type 2
  • Polyendocrine Autoimmune Syndrome, Type II
  • Polyendocrinopathy Candidiasis Ectodermal Dystrophy, Autoimmune
  • Polyendocrinopathy, Autoimmune
  • Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy, Autoimmune
  • Polyendocrinopathy-Candidiasis-Ectodermal-Dystrophy, Autoimmune
  • Polyendokrinopathien, Autoimmun- (DE)
  • Polyglandular Autoimmune Syndrome, Type 1
  • Polyglandular Autoimmune Syndrome, Type 2
  • Polyglandular Autoimmune Syndrome, Type 3
  • Polyglandular Autoimmune Syndrome, Type I
  • Polyglandular Deficiency Syndrome, Type 2
  • Polyglandular Type I Autoimmune Syndrome
  • Polyglandular Type II Autoimmune Syndrome
  • Polyglandular Type III Autoimmune Syndrome
  • Polyglanduläres Typ-I-Autoimmunsyndrom (DE)
  • Polyglanduläres Typ-II-Autoimmunsyndrom (DE)
  • Schmidt Syndrome
  • Schmidt's Syndrome
  • Schmidt-Syndrom (DE)
  • Syndrome, Schmidt
  • Syndrome, Schmidt's
AN

do not coordinate with specific endocrine disease term or CANDIDIASIS unless particularly discussed

AQL

BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI

DC

1

DX

19920101

HN

1992

MDA

19910502

MMR

20130708

MN

C19.787, C20.111.750

PM

1992

QB

http://purl.bioontology.org/ontology/MESH/Q000097, http://purl.bioontology.org/ontology/MESH/Q000175, http://purl.bioontology.org/ontology/MESH/Q000196, http://purl.bioontology.org/ontology/MESH/Q000151, http://purl.bioontology.org/ontology/MESH/Q000150, http://purl.bioontology.org/ontology/MESH/Q000191, http://purl.bioontology.org/ontology/MESH/Q000139, http://purl.bioontology.org/ontology/MESH/Q000534, http://purl.bioontology.org/ontology/MESH/Q000378, http://purl.bioontology.org/ontology/MESH/Q000532, http://purl.bioontology.org/ontology/MESH/Q000235, http://purl.bioontology.org/ontology/MESH/Q000652, http://purl.bioontology.org/ontology/MESH/Q000453, http://purl.bioontology.org/ontology/MESH/Q000178, http://purl.bioontology.org/ontology/MESH/Q000134, http://purl.bioontology.org/ontology/MESH/Q000276, http://purl.bioontology.org/ontology/MESH/Q000473, http://purl.bioontology.org/ontology/MESH/Q000451, http://purl.bioontology.org/ontology/MESH/Q000000981, http://purl.bioontology.org/ontology/MESH/Q000517, http://purl.bioontology.org/ontology/MESH/Q000382, http://purl.bioontology.org/ontology/MESH/Q000601, http://purl.bioontology.org/ontology/MESH/Q000821, http://purl.bioontology.org/ontology/MESH/Q000469, http://purl.bioontology.org/ontology/MESH/Q000523, http://purl.bioontology.org/ontology/MESH/Q000401, http://purl.bioontology.org/ontology/MESH/Q000201, http://purl.bioontology.org/ontology/MESH/Q000662, http://purl.bioontology.org/ontology/MESH/Q000266, http://purl.bioontology.org/ontology/MESH/Q000145, http://purl.bioontology.org/ontology/MESH/Q000188, http://purl.bioontology.org/ontology/MESH/Q000628, http://purl.bioontology.org/ontology/MESH/Q000209, http://purl.bioontology.org/ontology/MESH/Q000208, http://purl.bioontology.org/ontology/MESH/Q000503

SIB

http://purl.bioontology.org/ontology/MESH/D000071698, http://purl.bioontology.org/ontology/MESH/D015433, http://purl.bioontology.org/ontology/MESH/D062027, http://purl.bioontology.org/ontology/MESH/D001172, http://purl.bioontology.org/ontology/MESH/D010900, http://purl.bioontology.org/ontology/MESH/D013959, http://purl.bioontology.org/ontology/MESH/D001171, http://purl.bioontology.org/ontology/MESH/D008180, http://purl.bioontology.org/ontology/MESH/D003920, http://purl.bioontology.org/ontology/MESH/D056735, http://purl.bioontology.org/ontology/MESH/D006058, http://purl.bioontology.org/ontology/MESH/D001849, http://purl.bioontology.org/ontology/MESH/D010391, http://purl.bioontology.org/ontology/MESH/D003922, http://purl.bioontology.org/ontology/MESH/D005922, http://purl.bioontology.org/ontology/MESH/D010392, http://purl.bioontology.org/ontology/MESH/D006111, http://purl.bioontology.org/ontology/MESH/D016553, http://purl.bioontology.org/ontology/MESH/D004392, http://purl.bioontology.org/ontology/MESH/D019867, http://purl.bioontology.org/ontology/MESH/D053716, http://purl.bioontology.org/ontology/MESH/D010279, http://purl.bioontology.org/ontology/MESH/D000074079, http://purl.bioontology.org/ontology/MESH/D016736, http://purl.bioontology.org/ontology/MESH/D013967, http://purl.bioontology.org/ontology/MESH/D004701, http://purl.bioontology.org/ontology/MESH/D000224, http://purl.bioontology.org/ontology/MESH/D003874, http://purl.bioontology.org/ontology/MESH/D019693, http://purl.bioontology.org/ontology/MESH/D056648, http://purl.bioontology.org/ontology/MESH/D000077733, http://purl.bioontology.org/ontology/MESH/D000069281, http://purl.bioontology.org/ontology/MESH/D020274, http://purl.bioontology.org/ontology/MESH/D000307, http://purl.bioontology.org/ontology/MESH/D014383, http://purl.bioontology.org/ontology/MESH/D000744, http://purl.bioontology.org/ontology/MESH/D009879

TERMUI

T781325, T781369, T781326, T781367, T781323, T781368, T050550, T781327, T781328, T840969, T817906, T811989, T817905, T817904, T050547, T750782, T840967, T050546, T050549, T840966, T050548, T840962, T637908, T781370, T637907, T781371, T050545, T811992, T812003, T050544, T811993, T812005, T844117, T844116

TH

GHR (2014), NLM (2006), NLM (1992), ORD (2010), OMIM (2013), NLM (2010), NLM (2012)

cui

C0085860, C1535942, C0085859, C0085409

hasSTY

http://purl.bioontology.org/ontology/STY/T047

mapped from

http://purl.bioontology.org/ontology/MESH/C538274, http://purl.bioontology.org/ontology/MESH/C538273, http://purl.bioontology.org/ontology/MESH/C538275

tui

T047

Term relations