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Soluble Tumor Necrosis Factor Receptor Superfamily Member 8

Go to external page http://purl.obolibrary.org/obo/NCIT_C103890

Soluble tumor necrosis factor receptor superfamily member 8 (~85 kDa) is encoded by the human TNFRSF8 gene. This enzymatically processed protein may be involved in the inhibition of tumor necrosis factor ligand superfamily member 8 (CD30 ligand) binding to its cell surface-localized receptor. [ ]

Term info

Label

Soluble Tumor Necrosis Factor Receptor Superfamily Member 8

Synonyms
  • Soluble Ber-H2
  • Soluble CD30
  • Soluble CD30L Receptor
  • Soluble Ki-1
  • Soluble Ki-1 Antigen
  • Soluble Tumor Necrosis Factor Receptor Superfamily Member 8
  • sCD30
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

DesignNote

Elevated levels of soluble tumor necrosis factor receptor superfamily member 8 may be a marker for tumor burden or graft rejection., Soluble tumor necrosis factor receptor superfamily member 8 results from proteolytic processing of the full-length membrane-bound tumor necrosis factor receptor superfamily member 8 protein by disintegrin and metalloproteinase domain-containing protein 17. (J Immunol. 2000; 165:6703-9.)

Display Name

Soluble Tumor Necrosis Factor Receptor Superfamily Member 8

OMIM Number

153243

Preferred Name

Soluble Tumor Necrosis Factor Receptor Superfamily Member 8

Semantic Type

Amino Acid, Peptide, or Protein

Swiss Prot

P28908

UMLS CUI

C3641673

code

C103890