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I-Kappa-B Kinase

Go to external page http://purl.obolibrary.org/obo/NCIT_C104199

An enzyme complex that is involved in serine/threonine phosphorylation, inflammation and the regulation of the nuclear factor kappa-light-chain-enhancer of activated B cells protein complex. I-kappa-B kinase is comprised of three proteins, inhibitor of nuclear factor kappa-B kinase subunit alpha, beta and gamma. [ ]

Term info

Label

I-Kappa-B Kinase

Synonyms
  • I-Kappa-B Kinase
  • IKK
  • IKappaB Kinase
  • IkappaB Kinase Complex
  • Inhibitor of Nuclear Factor Kappa-B Kinase
  • Nuclear Factor NF-Kappa-B Inhibitor Kinase
  • Nuclear Factor NFKappaB Inhibitor Kinase
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

DesignNote

I-kappa-B kinase phosphorylates I-kappa B family proteins, which promotes signaling by NF-kappa-B complexes.

Display Name

I-Kappa-B Kinase

NCI META CUI

CL439178

Preferred Name

I-Kappa-B Kinase

Semantic Type

Amino Acid, Peptide, or Protein, Enzyme

code

C104199