Terminology Service for NFDI4Health
Major Vault Protein
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http://purl.obolibrary.org/obo/NCIT_C104704
Major vault protein (893 aa, ~100 kDa) is encoded by the human MVP gene. This protein plays a role in both the structure and function of vault ribonucleoprotein complexes. [ ]
Term info
Label
Major Vault Protein
Synonyms
- Lung Resistance-Related Protein
- MVP
- Major Vault Protein
Subsets
NCIT_C116977, NCIT_C142800, NCIT_C142799
Contributing Source
CTRP
DesignNote
The vault ribonucleoprotein particle is a huge cage structure (400 A x 670 A) of 12.9 MDa. It consists of a dimer of half-vaults, each half-vault is comprised of 39 identical major vault protein (MVP) chains, PARP4 and one or more vault RNAs (vRNAs). (UniProt)
Display Name
Major Vault Protein
OMIM Number
605088
Preferred Name
Major Vault Protein
Semantic Type
Amino Acid, Peptide, or Protein
Swiss Prot
Q14764
UMLS CUI
C0293442
code
C104704
Term relations
Subclass of:
- Structural Protein
- Gene_Product_Encoded_By_Gene some MVP Gene
- Gene_Product_Is_Physical_Part_Of some Ribonucleoprotein
- Gene_Product_Plays_Role_In_Biological_Process some Intracellular Transport
- Gene_Product_Has_Associated_Anatomy some Nucleus
- Gene_Product_Plays_Role_In_Biological_Process some Signal Transduction