Terminology Service for NFDI4Health
Negative Elongation Factor C/D
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http://purl.obolibrary.org/obo/NCIT_C105099
Negative elongation factor C/D (590 aa, ~66 kDa) is encoded by the human NELFCD gene. This protein is involved in transcriptional pausing. [ ]
Term info
Label
Negative Elongation Factor C/D
Synonyms
- NELF-C/D
- NELFCD
- Negative Elongation Factor C/D
- Negative Elongation Factor Proteins C and D
- TH1-Like Protein
- Trihydrophobin 1
Subsets
NCIT_C116977, NCIT_C142800, NCIT_C142799
Contributing Source
CTRP
DesignNote
Usage of alternative translation initiation sites results in the formation of two isoforms, NELF-C and NELF-D. NELF-D lacks the first 9 amino acids found in NELF-C. (EntrezGene and UniProt)
Display Name
Negative Elongation Factor C/D
OMIM Number
605297
Preferred Name
Negative Elongation Factor C/D
Semantic Type
Amino Acid, Peptide, or Protein
Swiss Prot
Q8IXH7
UMLS CUI
C1451170
code
C105099
Term relations
Subclass of:
- Transcription Regulatory Protein
- Gene_Product_Plays_Role_In_Biological_Process some Transcriptional Repression
- Gene_Product_Has_Biochemical_Function some Transcription Repressor/Corepressor
- Gene_Product_Encoded_By_Gene some NELFCD Gene
- Gene_Product_Plays_Role_In_Biological_Process some Transcription Elongation