Terminology Service for NFDI4Health

Lamina-Associated Polypeptide 2, Isoforms Beta/Gamma

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Lamina-associated polypeptide 2, isoforms beta/gamma (694 aa, ~75 kDa) is encoded by the human TMPO gene. This protein is involved in the mediation of nuclear structure. [ ]

Term info

Label

Lamina-Associated Polypeptide 2, Isoforms Beta/Gamma

Synonyms
  • LEM Domain Containing 4
  • Lamina-Associated Polypeptide 2
  • Lamina-Associated Polypeptide 2, Isoforms Beta/Gamma
  • TMPO
  • TP Beta/Gamma
  • TPRP Isoforms Beta/Gamma
  • Thymopoietin
  • Thymopoietin, Isoforms Beta/Gamma
  • Thymopoietin-Related Peptide Isoforms Beta/Gamma
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

DesignNote

Lamina-associated polypeptide 2, isoforms beta/gamma is cleaved to form 2 polypeptides: thymopoietin (TP, Splenin) and thymopentin (TP5). Both polypeptides play a role in T-cell function. (UniProt), Lamina-associated polypeptide 2, isoforms beta/gamma is a transmembrane protein in the inner nuclear membrane. (UniProt)

Display Name

Lamina-Associated Polypeptide 2, Isoforms Beta/Gamma

OMIM Number

188380

Preferred Name

Lamina-Associated Polypeptide 2, Isoforms Beta/Gamma

Semantic Type

Amino Acid, Peptide, or Protein

Swiss Prot

P42167

UMLS CUI

C3538882

code

C105103