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High Affinity Nerve Growth Factor Receptor Isoform TrkA-III

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High affinity nerve growth factor receptor isoform TrkA-III (698 aa, ~77 kDa) is encoded by the human NTRK1 gene. This protein is involved in constitutive signaling and tyrosine phosphorylation. [ ]

Term info

Label

High Affinity Nerve Growth Factor Receptor Isoform TrkA-III

Synonyms
  • EC 2.7.10.1
  • High Affinity Nerve Growth Factor Receptor Isoform TrkA-III
  • NTRK1 Isoform TrkA-III
  • Nerve Growth Factor Receptor Type 1 Isoform TrkA-III
  • Neurotrophic Tyrosine Kinase Receptor Type 1 Isoform TrkA-III
  • TRK1-Transforming Tyrosine Kinase Protein
  • TrkA-III
  • TrkAIII
  • Tropomyosin-Related Kinase A Isoform TrkA-III
  • Tyrosine Kinase Receptor A Isoform TrkA-III
  • Tyrosine Kinase Receptor Isoform TrkA-III
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

DesignNote

High Affinity Nerve Growth Factor Receptor Isoform TrkA-III isoform is specifically expressed by pluripotent neural stem and neural crest progenitors and its expression is stimulated by hypoxia. (UniProt), High affinity nerve growth factor receptor isoform TrkA-III does not bind NGF and does not interact with the adaptor molecules GRB2 and FRS2. (UniProt)

Display Name

High Affinity Nerve Growth Factor Receptor Isoform TrkA-III

OMIM Number

191315

Preferred Name

High Affinity Nerve Growth Factor Receptor Isoform TrkA-III

Semantic Type

Amino Acid, Peptide, or Protein, Receptor

Swiss Prot

P04629

UMLS CUI

C3538924

code

C105368