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CDGSH Iron-Sulfur Domain-Containing Protein 1

http://purl.obolibrary.org/obo/NCIT_C113135

CDGSH iron-sulfur domain-containing protein 1 (108 aa, ~12 kDa) is encoded by the human CISD1 gene. This protein is involved in both iron-sulfur cluster binding and the regulation of cell respiration. [ ]

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Term info

Label

CDGSH Iron-Sulfur Domain-Containing Protein 1

Synonyms

CDGSH Iron Sulfur Domain-Containing Protein 1
CDGSH Iron-Sulfur Domain-Containing Protein 1
MitoNEET
Mitochondrial Asn-Glu-Glu-Thr (NEET)
Zinc Finger CDGSH-Type Domain 1

DesignNote

CDGSH iron-sulfur domain-containing protein 1 binds the anti-diabetes drug, pioglitazone. This interaction stabilizes the iron-sulfur (2Fe-2s) cluster. (UniProt)

OMIM Number

611932

Preferred Name

CDGSH Iron-Sulfur Domain-Containing Protein 1

Semantic Type

Amino Acid, Peptide, or Protein

Swiss Prot

Q9NZ45

UMLS CUI

C2003363

code

C113135

Term relations

Subclass of:

Ligand Binding Protein
Gene_Product_Plays_Role_In_Biological_Process some Cell Respiration
Gene_Product_Has_Chemical_Classification some Transmembrane Protein
Gene_Product_Plays_Role_In_Biological_Process some Metal Ion Binding
Gene_Product_Encoded_By_Gene some CISD1 Gene
Gene_Product_Has_Associated_Anatomy some Outer Mitochondrial Membrane
Gene_Product_Has_Structural_Domain_Or_Motif some Transmembrane Domain