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Receptor-Activated SMAD

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A family of transcription factors that are activated by signaling mediated by tumor growth factor-beta (TGF-beta) superfamily ligand-receptor interactions. Once activated, R-SMADs play a role in the positive regulation of TGF-beta responsive gene expression. [ ]

Term info

Label

Receptor-Activated SMAD

Synonyms
  • R-SMAD
  • R-SMADs
  • Receptor-Activated SMAD
  • Receptor-Activated SMADs
  • Receptor-Regulated SMAD
  • Receptor-Regulated SMADs
  • rSMAD
  • rSMADs
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

DesignNote

The R-SMAD family includes SMAD1, SMAD2, SMAD3, SMAD5, and SMAD8.

Display Name

Receptor-Activated SMAD

Preferred Name

Receptor-Activated SMAD

Semantic Type

Amino Acid, Peptide, or Protein

UMLS CUI

C3828360

code

C113248