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NADH Dehydrogenase (Ubiquinone)

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A complex of over 40 proteins found in the inner mitochondrial membrane. This protein complex catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q10) and plays a role in the initiation of the mitochondrial electron transport chain. [ ]

Term info

Label

NADH Dehydrogenase (Ubiquinone)

Synonyms
  • Coenzyme Q Reductase
  • Complex 1 Dehydrogenase
  • Complex I
  • Complex I (Electron Transport Chain)
  • Complex I (Mitochondrial Electron Transport)
  • Complex I (NADH:Q1 Oxidoreductase)
  • DPNH-Coenzyme Q Reductase
  • DPNH-Ubiquinone Reductase
  • Dihydronicotinamide Adenine Dinucleotide-Coenzyme Q Reductase
  • EC 1.6.5.3
  • Electron Transfer Complex I
  • Mitochondrial Complex I
  • Mitochondrial Electron Transport Complex 1
  • Mitochondrial Electron Transport Complex I
  • Mitochondrial Respiratory Chain Complex I
  • NADH Coenzyme Q1 Reductase
  • NADH Dehydrogenase (Ubiquinone)
  • NADH-CoQ Oxidoreductase
  • NADH-CoQ Reductase
  • NADH-Coenzyme Q Oxidoreductase
  • NADH-Coenzyme Q Reductase
  • NADH-Q6 Oxidoreductase
  • NADH-Ubiquinone Oxidoreductase
  • NADH-Ubiquinone Reductase
  • NADH-Ubiquinone-1 Reductase
  • NADH2 Dehydrogenase (Ubiquinone)
  • NADH:Ubiquinone Oxidoreductase
  • NADH:Ubiquinone Oxidoreductase Complex
  • NADH:Ubiquinone Reductase (H(+)-Translocating)
  • Reduced Nicotinamide Adenine Dinucleotide-Coenzyme Q Reductase
  • Respiratory Complex I
  • Type 1 Dehydrogenase
  • Ubiquinone Reductase
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

DesignNote

There are 14 core subunits found in all organisms and over 30 accessory subunits, which may play a role in the assembly or stability of the complex. Of the 14 core subunits, 7 are encoded by nuclear genes and 7 are encoded by mitochondrial genes.

Display Name

NADH Dehydrogenase (Ubiquinone)

Preferred Name

NADH Dehydrogenase (Ubiquinone)

Semantic Type

Amino Acid, Peptide, or Protein, Enzyme

UMLS CUI

C0171406

code

C118184