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Proepiregulin

Go to external page http://purl.obolibrary.org/obo/NCIT_C118410

Proepiregulin (169 aa, ~19 kDa) is encoded by the human EREG gene. This protein plays a role in the promotion of cell proliferation. [ ]

Term info

Label

Proepiregulin

Synonyms
  • EREG
  • Epiregulin
  • Proepiregulin
DesignNote

The active form of the growth factor, epiregulin, is produced by two proteolytic cleavage events that remove 59 N-terminal amino acids and 61 amino acids from the C-terminus of proepiregulin. The precursor is a type I membrane protein and the mature form is a secreted protein. (UniProt)

OMIM Number

602061

Preferred Name

Proepiregulin

Semantic Type

Amino Acid, Peptide, or Protein

Swiss Prot

O14944

UMLS CUI

C3888282

code

C118410