Terminology Service for NFDI4Health
Protransforming Growth Factor Alpha
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http://purl.obolibrary.org/obo/NCIT_C118440
Protransforming growth factor alpha (160 aa, ~17 kDa) is encoded by the human TGFA gene. This protein plays a role in cell proliferation. [ ]
Term info
Label
Protransforming Growth Factor Alpha
Synonyms
- Pro-Transforming Growth Factor Alpha
- Protransforming Growth Factor Alpha
DesignNote
The active form of the growth factor, transforming growth factor alpha, is produced when proteolytic cleavage removes 39 amino acids from the N-terminus and 71 amino acids from the C-terminus of protransforming growth factor alpha. The precursor is a transmembrane protein and the mature form is a secreted protein. (UniProt)
OMIM Number
190170
Preferred Name
Protransforming Growth Factor Alpha
Semantic Type
Amino Acid, Peptide, or Protein
Swiss Prot
P01135
UMLS CUI
C0072502
code
C118440