Terminology Service < Semantic Lookup Platform

CTX

http://purl.obolibrary.org/obo/NCIT_C120031

This polypeptide is comprised of the carboxy-terminal portions of fibrillar collagen, which are joined through trivalent crosslinks and released during the degradation of mature type I collagen by cathepsin K. Serum concentrations of these peptides can be correlated with the rate of bone metabolism. [ ]

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Term info

Label

CTX

Synonyms

C-Telopeptide
C-Terminal Telopeptide Type 1 Collagen
C-Terminal Telopeptide Type I Collagen
CTX
CTX-I
CTXI
Collagen Type 1 Cross-linked C-Telopeptide
Cross-Linked C-Terminal Telopeptide of Type I Collagen

Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

Contributing Source

CTRP

DesignNote

Triple helical collagen is constructed from more than one gene product; thus, C-telopeptides arise from heterogeneous sources.

Display Name

CTX

Preferred Name

CTX

Semantic Type

Amino Acid, Peptide, or Protein

UMLS CUI

C0631180

code

C120031

Term relations

Subclass of:

Collagen
Gene_Product_Is_Physical_Part_Of some Type I Collagen
Gene_Product_Has_Chemical_Classification some Protein Fragment
Gene_Product_Encoded_By_Gene some Collagen Gene
Gene_Product_Has_Organism_Source some Human