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Rhizoxin

Go to external page http://purl.obolibrary.org/obo/NCIT_C1218

A macrocyclic lactone. Rhizoxin binds to tubulin and inhibits microtubule assembly, thereby inducing cytotoxicity. This agent also may inhibit endothelial cell-induced angiogenic activity, which may result in decreased tumor cell proliferation. (NCI04) [ ]

Term info

Label

Rhizoxin

Synonyms
  • Rhizoxin
  • WF-1360
  • rhizoxin
Subsets

NCIT_C128784, NCIT_C157711, NCIT_C157712

ALT DEFINITION

A substance that is being studied in the treatment of cancer. It comes from a fungus and is similar to vinca alkaloid drugs. It belongs to the family of drugs called antimitotic agents.

CAS Registry

90996-54-6

NSC Code

332598

Preferred Name

Rhizoxin

Semantic Type

Antibiotic, Organic Chemical

UMLS CUI

C0073184

code

C1218