Terminology Service for NFDI4Health
Leucine-Rich Repeats and Immunoglobulin-Like Domains Protein Family
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http://purl.obolibrary.org/obo/NCIT_C122769
A family of membrane bound proteins comprised of 15 leucine-rich repeats that are flanked both N- and C- terminally by cysteine-rich regions, three C2-type immunoglobulin-like domains, a transmembrane domain, and a cytoplasmic tail. The members of this protein family may be involved in the suppression of growth factor receptor signaling. [ ]
Term info
Label
Leucine-Rich Repeats and Immunoglobulin-Like Domains Protein Family
Synonyms
- LIG
- LIG Family
- LRIG
- LRIG Family
- Leucine-Rich Repeats and Immunoglobulin-Like Domains Protein
- Leucine-Rich Repeats and Immunoglobulin-Like Domains Protein Family
Subsets
NCIT_C116977, NCIT_C142800, NCIT_C142799
Contributing Source
CTRP
Display Name
Leucine-Rich Repeats and Immunoglobulin-Like Domains Protein Family
Preferred Name
Leucine-Rich Repeats and Immunoglobulin-Like Domains Protein Family
PubMedID Primary Reference
15203213
Semantic Type
Amino Acid, Peptide, or Protein
UMLS CUI
C4050247
code
C122769
Term relations
Subclass of:
- Protein Family
- Gene_Product_Has_Structural_Domain_Or_Motif some Cysteine-Rich Domain
- Gene_Product_Has_Structural_Domain_Or_Motif some Cytoplasmic Domain
- Gene_Product_Has_Structural_Domain_Or_Motif some Immunoglobulin-Like C2-Type Domain
- Gene_Product_Has_Structural_Domain_Or_Motif some Leucine-Rich Repeat
- Gene_Product_Has_Structural_Domain_Or_Motif some Transmembrane Domain