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BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.T315I

Go to external page http://purl.obolibrary.org/obo/NCIT_C123846

A fusion protein encoded by the BCR/ABL1 fusion gene with ABL1 NM_005157.4:c.944C>T mutation. This protein is comprised of the N-terminus of the breakpoint cluster region protein fused to almost the entire tyrosine-protein kinase ABL1 protein where the threonine at position 315 of the ABL1 protein has been replaced by isoleucine. [ ]

Term info

Label

BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.T315I

Synonyms
  • BCR-ABL T315I Mutation
  • BCR-ABL Thr315Ile Mutation
  • BCR-ABL1 T315I Mutation
  • BCR-ABL1 Thr315Ile Mutation
  • BCR/ABL Fusion Protein with T315I
  • BCR/ABL Fusion Protein with Thr315Ile
  • BCR/ABL T315I Mutation
  • BCR/ABL Thr315Ile Mutation
  • BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.T315I
  • BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.Thr315Ile
  • BCR/ABL1 Fusion Protein with NP_005148.2:p.T315I
  • BCR/ABL1 Fusion Protein with NP_005148.2:p.Thr315Ile
  • BCR/ABL1 T315I Mutation
  • BCR/ABL1 Thr315Ile Mutation
  • T315I
  • T315I Mutation
Subsets

NCIT_C118168, NCIT_C116977, NCIT_C142800, NCIT_C142799

DesignNote

The position of the amino acid substitution is denoted by its location in the tyrosine-protein kinase ABL1 protein sequence (NCBI Reference Sequence: NP_005148.2) and not its location in the fusion protein.

Display Name

BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.T315I

NCI META CUI

CL373038

Preferred Name

BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.T315I

Related To Genetic Biomarker

http://purl.obolibrary.org/obo/NCIT_C17346, http://purl.obolibrary.org/obo/NCIT_C18455

Semantic Type

Amino Acid, Peptide, or Protein

code

C123846