Terminology Service for NFDI4Health

Protachykinin-1

Go to external page http://purl.obolibrary.org/obo/NCIT_C124856


Protachykinin-1 (129 aa, ~15 kDa) is encoded by the human TAC1 gene. This protein is involved in neuronal excitation, behavioral responses, and smooth muscle contraction. [ ]

Term info

Label

Protachykinin-1

Synonyms
  • PPT
  • Preprotachykinin
  • Protachykinin
  • Protachykinin 1
  • Protachykinin-1
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

DesignNote

Protachykinin-1 is cleaved into the following 7 biologically active peptide chains: Substance P, Neurokinin A (NKA, Neurokinin alpha), Neuromedin L, Substance K, Neuropeptide K (NPK), Neuropeptide gamma, and C-terminal-flanking peptide. (UniProt)

Display Name

Protachykinin-1

OMIM Number

162320

Preferred Name

Protachykinin-1

Semantic Type

Amino Acid, Peptide, or Protein

Swiss Prot

P20366

UMLS CUI

C0071942

code

C124856