Terminology Service for NFDI4Health
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Cytotoxic T-Lymphocyte

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Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed lymphocyte cultures (MLC), in vivo during a graft-versus-host (GVH) reaction, or after immunization with an allograft, tumor cell or virally transformed or chemically modified target cell. These cells are distinct from natural killer cells and from killer cells mediating antibody-dependent cell cytotoxicity. [ ]

Term info

Label

Cytotoxic T-Lymphocyte

Synonyms
  • CTL
  • Cytolytic T-Cell
  • Cytotoxic T Cell
  • Cytotoxic T Cells
  • Cytotoxic T-Lymphocyte
  • Cytotoxic T-Lymphocytes
  • T-Lymphocyte, Cytotoxic
  • T-Lymphocytes, Cytotoxic
  • cytotoxic T cell
  • cytotoxic T lymphocyte
  • killer T cell
Subsets

NCIT_C116977, NCIT_C142799

ALT DEFINITION

A type of immune cell that can kill certain cells, including foreign cells, cancer cells, and cells infected with a virus. Cytotoxic T lymphocytes can be separated from other blood cells, grown in the laboratory, and then given to a patient to kill cancer cells. A cytotoxic T lymphocyte is a type of white blood cell and a type of lymphocyte.

Display Name

Cytotoxic T-Lymphocyte

Legacy Concept Name

Cytotoxic_T-Lymphocyte

Preferred Name

Cytotoxic T-Lymphocyte

UMLS CUI

C0039195

code

C12543

Term relations

Related from:
Chemical_Or_Drug_Affects_Cell_Type_Or_Tissue