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Autophagy-Related Protein 13

Go to external page http://purl.obolibrary.org/obo/NCIT_C126137

Autophagy-related protein 13 (517 aa, ~57 kDa) is encoded by the human ATG13 gene. This protein plays a role in the modulation of autophagy. [ ]

Term info

Label

Autophagy-Related Protein 13

Synonyms
  • ATG13
  • Autophagy-Related Protein 13
  • PARATARG 8
  • Paraprotein Target 8
  • Paratarg-8
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

DesignNote

Autophagy-related protein 13 (ATG13) appears to be phosphorylated by phosphokinase C-zeta (PRKCZ) and dephosphorylated by phosphatase-2A (PP2A). Mutations that inactivate the PP2A catalytic subunit may be associated with hyperphosphorylation of ATG13 and may play a role in the pathogenesis of monoclonal gammopathy of unknown significance (MGUS), Waldenstrom macroglobulinemia, and multiple myeloma. (OMIM)

Display Name

Autophagy-Related Protein 13

NCI META CUI

CL504720

OMIM Number

615088

Preferred Name

Autophagy-Related Protein 13

Semantic Type

Amino Acid, Peptide, or Protein

Swiss Prot

O75143

code

C126137