Terminology Service for NFDI4Health
Serine Palmitoyltransferase 1
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http://purl.obolibrary.org/obo/NCIT_C127890
Serine palmitoyltransferase 1 (473 aa, ~53 kDa) is encoded by the human SPTLC1 gene. This protein plays a role in the biosynthesis of sphingolipids. [ ]
Term info
Label
Serine Palmitoyltransferase 1
Synonyms
- EC 2.3.1.50
- LCB 1
- Long Chain Base Biosynthesis Protein 1
- SPT 1
- SPT1
- Serine C-Palmitoyltransferase
- Serine Palmitoyltransferase 1
- Serine-Palmitoyl-CoA Transferase 1
Subsets
NCIT_C116977, NCIT_C142800, NCIT_C142799
Contributing Source
CTRP
DesignNote
Serine palmitoyltransferase 1 forms a heterodimer with either serine palmitoyltransferase 2 or serine palmitoyltransferase 3 to form the catalytic core of the serine palmitoyltransferase (SPT) complex. (UniProt)
Display Name
Serine Palmitoyltransferase 1
OMIM Number
605712
Preferred Name
Serine Palmitoyltransferase 1
Semantic Type
Amino Acid, Peptide, or Protein, Enzyme
Swiss Prot
O15269
UMLS CUI
C1453940
code
C127890
Term relations
Subclass of:
- Acyltransferase
- Gene_Product_Has_Chemical_Classification some Transmembrane Protein
- Gene_Product_Encoded_By_Gene some SPTLC1 Gene
- Gene_Product_Plays_Role_In_Biological_Process some Lipid Metabolic Process
- Gene_Product_Has_Associated_Anatomy some Membrane of the Rough Endoplasmic Reticulum
- Gene_Product_Has_Associated_Anatomy some Membrane of the Smooth Endoplasmic Reticulum
- Gene_Product_Is_Element_In_Pathway some Sphingolipid Metabolism Pathway
- Gene_Product_Has_Structural_Domain_Or_Motif some Transmembrane Domain