Terminology Service for NFDI4Health

Platelet-Derived Growth Factor-AB

Go to external page http://purl.obolibrary.org/obo/NCIT_C128286


A disulfide-linked heterodimeric protein complex comprised of one platelet-derived growth factor subunit A and one platelet-derived growth factor subunit B. This dimeric growth factor binds to a heterodimeric receptor comprised of one platelet-derived growth factor receptor alpha and one platelet-derived growth factor receptor beta. Ligand binding activates the intrinsic tyrosine-protein kinase activity of the receptor complex and initiates signal transduction pathways. [ ]

Term info

Label

Platelet-Derived Growth Factor-AB

Synonyms
  • PDGF-AB
  • Platelet-Derived Growth Factor-AB
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

Display Name

Platelet-Derived Growth Factor-AB

Preferred Name

Platelet-Derived Growth Factor-AB

Semantic Type

Amino Acid, Peptide, or Protein

UMLS CUI

C0381163

code

C128286