Platelet-Derived Growth Factor-BB
A disulfide-linked homodimeric protein complex comprised of 2 platelet-derived growth factor subunit B proteins. This dimeric growth factor binds to a homodimeric receptor comprised of two platelet-derived growth factor receptor beta proteins. Ligand binding activates the intrinsic tyrosine-protein kinase activity of the receptor complex and initiates signal transduction pathways. [ ]
Term info
Platelet-Derived Growth Factor-BB
- PDGF-BB
- Platelet-Derived Growth Factor-BB
NCIT_C116977, NCIT_C142800, NCIT_C142799
CTRP
Platelet-Derived Growth Factor-BB
Platelet-Derived Growth Factor-BB
Amino Acid, Peptide, or Protein
C0246681
C128287
Term relations
- Protein or Riboprotein Complex
- Gene_Product_Plays_Role_In_Biological_Process some Cell Proliferation
- Gene_Product_Has_Biochemical_Function some Growth Factor
- Gene_Product_Has_Biochemical_Function some Platelet-Derived Growth Factor
- Gene_Product_Plays_Role_In_Biological_Process some Receptor Signaling
- Gene_Product_Has_Associated_Anatomy some Extracellular Space