Terminology Service for NFDI4Health

Platelet-Derived Growth Factor-BB

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A disulfide-linked homodimeric protein complex comprised of 2 platelet-derived growth factor subunit B proteins. This dimeric growth factor binds to a homodimeric receptor comprised of two platelet-derived growth factor receptor beta proteins. Ligand binding activates the intrinsic tyrosine-protein kinase activity of the receptor complex and initiates signal transduction pathways. [ ]

Term info

Label

Platelet-Derived Growth Factor-BB

Synonyms
  • PDGF-BB
  • Platelet-Derived Growth Factor-BB
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

Display Name

Platelet-Derived Growth Factor-BB

Preferred Name

Platelet-Derived Growth Factor-BB

Semantic Type

Amino Acid, Peptide, or Protein

UMLS CUI

C0246681

code

C128287