Terminology Service for NFDI4Health

Androgen Receptor Splice Variant 3

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Androgen receptor protein that is comprised of the amino acids encoded by exons 1-3 and those encoded by cryptic exon 3 (CE3) of the human AR gene. This variant protein contains nuclear receptor transcriptional activation and DNA binding domains and is missing the hinge region and the nuclear receptor ligand binding and activation function-2 domains. Expression of this variant is associated with both a constitutively active, gain-of-function phenotype and prostate cancer. [ ]

Term info

Label

Androgen Receptor Splice Variant 3

Synonyms
  • AR-v7
  • AR3
  • Androgen Receptor Splice Variant 3
  • Androgen Receptor Splice Variant 7
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

Display Name

Androgen Receptor Splice Variant 3

NCI META CUI

CL509601

OMIM Number

313700

Preferred Name

Androgen Receptor Splice Variant 3

Semantic Type

Amino Acid, Peptide, or Protein

Swiss Prot

P10275

code

C128292