Terminology Service for NFDI4Health
Tumor Protein 63 Isoform 2
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http://purl.obolibrary.org/obo/NCIT_C128298
Tumor protein 63 isoform 2 (586 aa, ~66 kDa) is encoded by the human TP63 gene. This protein plays a role in the mediation of both transcription and skin development. [ ]
Term info
Label
Tumor Protein 63 Isoform 2
Synonyms
- Delta Np63 Alpha
- Delta-N p63-Alpha
- DeltaN-Alpha
- DeltaNp63 Alpha
- P51delNalpha
- Tumor Protein 63 Isoform 2
- p51
Subsets
NCIT_C116977, NCIT_C142800, NCIT_C142799
Contributing Source
CTRP
DesignNote
Tumor protein 63 isoform 2 is the product of an alternative promoter and start codon located in exon 3 of the human TP63 gene. It also has an N-terminally truncated transactivation domain. Expression of isoform 2 may be tissue specific and aberrant expression may be associated with head and neck squamous cell carcinoma. (Atlas of Genetics and Cytogenetics in Oncology and Haematology)
Display Name
Tumor Protein 63 Isoform 2
NCI META CUI
CL512081
OMIM Number
603273
Preferred Name
Tumor Protein 63 Isoform 2
Semantic Type
Amino Acid, Peptide, or Protein
Swiss Prot
Q9H3D4
code
C128298
Term relations
Subclass of:
- TP63 Gene Product
- Gene_Product_Plays_Role_In_Biological_Process some Histogenic Process
- Gene_Product_Plays_Role_In_Biological_Process some DNA Binding
- Gene_Product_Encoded_By_Gene some TP63 Gene
- Gene_Product_Plays_Role_In_Biological_Process some Transcriptional Regulation
- Gene_Product_Has_Organism_Source some Human