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Antisense Oligonucleotides

Go to external page http://purl.obolibrary.org/obo/NCIT_C1291

Antisense Oligonucleotides, short synthetic segments of DNA or RNA, designed with a sequence complimentary to a specific mRNA that target and bind with mRNA, causing inhibition of translation or overexpression of the protein encoded by the mRNA. [ ]

Term info

Label

Antisense Oligonucleotides

Synonyms
  • AS ODNs
  • Antisense Agents
  • Antisense Oligonucleotides
  • Gene Expression Inhibitor
  • antisense agent
  • antisense oligonucleotide
ALT DEFINITION

Small pieces of DNA or RNA that can bind to specific molecules of RNA. This blocks the ability of the RNA to make a protein or work in other ways. Antisense agents may be used to block the production of proteins needed for cell growth. They are being studied in the treatment of several types of cancer.

Legacy Concept Name

Antisense_Agent

Preferred Name

Antisense Oligonucleotides

Semantic Type

Nucleic Acid, Nucleoside, or Nucleotide, Chemical Viewed Functionally

UMLS CUI

C4018803

code

C1291

Term relations

Subclass of: