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BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.E255V

Go to external page http://purl.obolibrary.org/obo/NCIT_C131015

A fusion protein encoded by the BCR/ABL1 fusion gene with ABL1 NM_005157.4:c.764A>T mutation. This protein is comprised of the N-terminus of the breakpoint cluster region protein fused to almost the entire tyrosine-protein kinase ABL1 protein where the glutamic acid at position 255 of the ABL1 protein has been replaced by valine. [ ]

Term info

Label

BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.E255V

Synonyms
  • BCR-ABL E255V Mutation
  • BCR-ABL Glu255Val Mutation
  • BCR-ABL1 E255V Mutation
  • BCR-ABL1 Glu255Val Mutation
  • BCR/ABL E255V Mutation
  • BCR/ABL Fusion Protein with E255V
  • BCR/ABL Fusion Protein with Glu255Val
  • BCR/ABL Glu255Val Mutation
  • BCR/ABL1 E255V Mutation
  • BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.E255V
  • BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.Glu255Val
  • BCR/ABL1 Fusion Protein with NP_005148.2:p.E255V
  • BCR/ABL1 Fusion Protein with NP_005148.2:p.Glu255Val
  • BCR/ABL1 Glu255Val Mutation
  • E255V
DesignNote

The position of the amino acid substitution is denoted by its location in the tyrosine-protein kinase ABL1 protein sequence (NCBI Reference Sequence: NP_005148.2) and not its location in the fusion protein.

NCI META CUI

CL513778

Preferred Name

BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.E255V

Related To Genetic Biomarker

http://purl.obolibrary.org/obo/NCIT_C17346, http://purl.obolibrary.org/obo/NCIT_C18455

Semantic Type

Amino Acid, Peptide, or Protein

code

C131015