Terminology Service for NFDI4Health
WD Repeat-Containing Protein 5
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http://purl.obolibrary.org/obo/NCIT_C132136
WD repeat-containing protein 5 (334 aa, ~37 kDa) is encoded by the human WDR5 gene. This protein plays a role in post-translational modification of histone proteins. [ ]
Term info
Label
WD Repeat-Containing Protein 5
Synonyms
- BMP2-Induced 3-kb Gene Protein
- Cilia and Flagella Associated Protein 89
- WD Repeat-Containing Protein 5
- WDR5
DesignNote
WD repeat-containing protein 5 is a core member of the COMPASS histone H3 Lys4 (H3K4) MLL (1-4) methyltransferase complex. (Cell Reports. 2016; 16:133-147.), WD repeat-containing protein 5 is part of the WD repeat-containing protein 5 Ada2a-containing (ATAC) histone acetyltransferase (HAT) complex and several histone methyltransferase complexes. (UniProt)
OMIM Number
609012
Preferred Name
WD Repeat-Containing Protein 5
Semantic Type
Amino Acid, Peptide, or Protein
Swiss Prot
P61964
UMLS CUI
C1610219
code
C132136