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E2 Ubiquitin-Conjugating Enzyme

Go to external page http://purl.obolibrary.org/obo/NCIT_C133711

An aminoacyltransferase that catalyzes the second step in the ubiquitination reaction via the transfer of activated ubiquitin from an E1 ubiquitin-activating enzyme to itself via transthioesterification. [ ]

Term info

Label

E2 Ubiquitin-Conjugating Enzyme

Synonyms
  • E2 Ubiquitin-Conjugating Enzyme
  • Ubiquitin Carrier Enzyme
  • Ubiquitin Carrier Protein
  • Ubiquitin-Conjugating Enzyme
  • Ubiquitin-Conjugating Enzyme E2
DesignNote

The IUBMB has recategorized E2 ubiquitin-conjugating enzymes as transferases (EC 2). There are 3 categories of E2 enzymes: E3-dependent (EC 2.3.2.23), E3-independent (EC 2.3.2.24) and N-terminal E2 Ubiquitin-Conjugating enzymes (EC 2.3.2.25) (2015)

Preferred Name

E2 Ubiquitin-Conjugating Enzyme

Semantic Type

Amino Acid, Peptide, or Protein, Enzyme

UMLS CUI

C0077670

code

C133711