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Pyruvate Kinase PKM Isoform M2 Dimer

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A homodimer of the pyruvate kinase PKM isoform M2. This enzyme complex promotes cellular metabolism and is overexpressed in tumors. [ ]

Term info

Label

Pyruvate Kinase PKM Isoform M2 Dimer

Synonyms
  • M2-PK
  • Pyruvate Kinase PKM Isoform M2 Dimer
  • Tumor M2-PK
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

DesignNote

M2-PK may be used as a biomarker for colorectal cancer in fecal testing or as a marker for pancreatic, gastric, esophageal, colorectal and cholangiocellular cancer in plasma screening.

Display Name

Pyruvate Kinase PKM Isoform M2 Dimer

NCI META CUI

CL524466

Preferred Name

Pyruvate Kinase PKM Isoform M2 Dimer

Semantic Type

Amino Acid, Peptide, or Protein, Enzyme

code

C136626