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Natriuretic Peptides A

Go to external page http://purl.obolibrary.org/obo/NCIT_C139910

Natriuretic peptides A (153 aa, ~17 kDa) is encoded by the human NPPA gene. This protein is involved in uterine artery remodeling, trophoblast invasion, natriuresis, diuresis, and vasodilation. [ ]

Term info

Label

Natriuretic Peptides A

Synonyms
  • Atrial Natriuretic Polypeptides
  • CDD
  • CDP
  • Cardiodilatin
  • Cardiodilatin-Related Peptide
  • NPPA
  • Natriuretic Peptide Precursor A
  • Natriuretic Peptides A
  • Prepronatriodilatin
DesignNote

Natriuretic peptides A is cleaved on the C-terminal side of amino acid 123 by atrial natriuretic peptide-converting enzyme (Corin), which releases the 28 amino acid active hormone atrial natriuretic factor (ANF; atrionatriuretic factor, atriopeptin, atrial natriuretic peptide; ANP; cardionatrin). ANF can be cleaved by macrophage metalloelastase (MME), which promotes degradation of the hormone. (UniProt)

OMIM Number

108780

Preferred Name

Natriuretic Peptides A

Semantic Type

Hormone, Amino Acid, Peptide, or Protein

Swiss Prot

P01160

UMLS CUI

C1258629

code

C139910