Terminology Service for NFDI4Health
Beta-2-Glycoprotein 1
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http://purl.obolibrary.org/obo/NCIT_C142155
Beta-2-glycoprotein 1 (345 aa, ~38 kDa) is encoded by the human APOH gene. This protein is involved in binding to phospholipids, glycosaminoglycans and other negatively charged substances. [ ]
Term info
Label
Beta-2-Glycoprotein 1
Synonyms
- APC Inhibitor
- APOH
- Activated Protein C-Binding Protein
- Anticardiolipin Cofactor
- Apo-H
- Apolipoprotein H
- B2GPI
- Beta(2)GPI
- Beta-2 Glycoprotein 1
- Beta-2-Glycoprotein 1
- Beta-2-Glycoprotein I
DesignNote
Beta-2-glycoprotein 1 may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome. (EntrezGene)
NCI META CUI
CL524123
OMIM Number
138700
Preferred Name
Beta-2-Glycoprotein 1
Semantic Type
Amino Acid, Peptide, or Protein
Swiss Prot
P02749
code
C142155
Term relations
Subclass of:
- Ligand Binding Protein
- Gene_Product_Has_Associated_Anatomy some Extracellular Space
- Gene_Product_Has_Structural_Domain_Or_Motif some Sushi Domain
- Gene_Product_Plays_Role_In_Biological_Process some Coagulation Process
- Gene_Product_Plays_Role_In_Biological_Process some Phospholipid Binding
- Gene_Product_Plays_Role_In_Biological_Process some Heparin Binding