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APOBEC1 Complementation Factor

http://purl.obolibrary.org/obo/NCIT_C143033

APOBEC1 complementation factor (594 aa, ~65 kDa) is encoded by the human A1CF gene. This protein is involved in binding to and metabolism of APOB mRNA. Missense mutations in the gene may be associated with melanoma and other neoplastic diseases. [ ]

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Term info

Label

APOBEC1 Complementation Factor

Synonyms

A1CF
APOBEC-1 Stimulating Protein
APOBEC1 Complementation Factor
APOBEC1-Stimulating Protein
Apo-B RNA Editing Protein

DesignNote

APOBEC1 complementation factor may be responsible for docking the catalytic APOBEC1 complex with APOB mRNA.

Preferred Name

APOBEC1 Complementation Factor

Semantic Type

Amino Acid, Peptide, or Protein

Swiss Prot

Q9NQ94

UMLS CUI

C0104364

code

C143033

Term relations

Subclass of:

RNA Binding Protein
Gene_Product_Has_Associated_Anatomy some Heterochromatin
Gene_Product_Plays_Role_In_Biological_Process some RNA Processing
Gene_Product_Encoded_By_Gene some A1CF Gene
Gene_Product_Has_Associated_Anatomy some Nucleus
Gene_Product_Has_Structural_Domain_Or_Motif some RNA Recognition Motif
Gene_Product_Plays_Role_In_Biological_Process some RNA Binding