Terminology Service for NFDI4Health
Interleukin-23
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http://purl.obolibrary.org/obo/NCIT_C147535
A heterodimeric cytokine composed of interleukin-12 subunit beta and interleukin-23 subunit alpha. This complex binds to the interleukin-23 receptor complex, which activates the JAK-STAT signaling pathway and modulates the proliferation, differentiation and effector functions of T-lymphocytes, natural killer cells and some myeloid lineage cells. [ ]
Term info
Label
Interleukin-23
Synonyms
- IL-23
- IL23
- Interleukin 23
- Interleukin-23
NCI META CUI
CL546020
Preferred Name
Interleukin-23
Semantic Type
Amino Acid, Peptide, or Protein
code
C147535
Term relations
Subclass of:
- Protein or Riboprotein Complex
- Gene_Product_Plays_Role_In_Biological_Process some NK Cell Activation
- Gene_Product_Plays_Role_In_Biological_Process some Cytokine Signaling
- Gene_Product_Plays_Role_In_Biological_Process some T-Cell Activation
- Gene_Product_Plays_Role_In_Biological_Process some Antimicrobial Effect
- Gene_Product_Has_Biochemical_Function some Interleukin