Terminology Service for NFDI4Health
Interleukin-23 Receptor Complex
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http://purl.obolibrary.org/obo/NCIT_C147560
A heterodimeric complex composed of interleukin-12 receptor subunit beta-1 and interleukin-23 receptor. This receptor complex binds to interleukin-23, which activates the JAK-STAT signaling pathway and modulates the activation of T-lymphocytes, natural killer cells and some myeloid lineage cells. [ ]
Term info
Label
Interleukin-23 Receptor Complex
Synonyms
- IL-23 Receptor
- IL-23R
- IL23R
- IL23R/IL12RB1 Complex
- Interleukin 23 Receptor
- Interleukin-23 Receptor
- Interleukin-23 Receptor Complex
Preferred Name
Interleukin-23 Receptor Complex
Semantic Type
Amino Acid, Peptide, or Protein
UMLS CUI
C3156590
code
C147560
Term relations
Subclass of:
- Protein or Riboprotein Complex
- Gene_Product_Plays_Role_In_Biological_Process some NK Cell Activation
- Gene_Product_Plays_Role_In_Biological_Process some Cytokine Signaling
- Gene_Product_Plays_Role_In_Biological_Process some T-Cell Activation
- Gene_Product_Has_Biochemical_Function some Cytokine Receptor
- Gene_Product_Plays_Role_In_Biological_Process some Antimicrobial Effect