Terminology Service for NFDI4Health
Activating EML4/ALK Gene Mutation
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http://purl.obolibrary.org/obo/NCIT_C150436
A change in the nucleotide sequence of the ALK portion of the EML4/ALK fusion gene that that results in constitutive activation of the EML4/ALK fusion protein and its downstream signaling pathways. These mutations are associated with increased oncogenic potential. [ ]
Term info
Label
Activating EML4/ALK Gene Mutation
Synonyms
- Activating EML4-ALK Fusion Gene Mutation
- Activating EML4-ALK Gene Mutation
- Activating EML4-ALK Mutation
- Activating EML4/ALK Fusion Gene Mutation
- Activating EML4/ALK Gene Mutation
- Activating EML4/ALK Mutation
Subsets
NCIT_C116977, NCIT_C142800, NCIT_C142799
Contributing Source
CTRP
Display Name
Activating EML4/ALK Gene Mutation
NCI META CUI
CL552232
Preferred Name
Activating EML4/ALK Gene Mutation
Semantic Type
Cell or Molecular Dysfunction
code
C150436